Enthusiastic, spoilery review of Make It Good from someone who doesn’t generally seem to be a big fan of IF.
Cellcraft, an RTS-style game about cellular biology, from the creator of Super Energy Apocalypse. More thorough review to follow later, but the short version is: I think the tutorial is paced wrong, and the interface has a few dozen things that I would tweak. On the other hand, by the end I was thoroughly enjoying this despite the quirks, and recalling some things about golgi bodies and the endoplasmic reticulum that I haven’t thought about for quite a while. And the silly, cute story provides a bit of motivation for the whole thing.
Emily Short's Interactive Storytelling 